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Investigating applications for humanized mouse models in preclinical research
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In an effort to understand human health and disease, researchers frequently make use of animal models. In the field of cancer research, mouse models are often the system of choice. However, there are sufficient differences between humans and mice that interpretation of the results can be difficult and even inaccurate. Endowing a mouse with a partially humanized immune system can go some way to circumventing this issue, providing a powerful tool for testing therapies against a variety of human diseases, including many cancers.
Join this conversation with Dr. Manfred Kraus, who will provide his personal take on the important role that humanized mouse models can play in preclinical research.
[Music: Ice Climb/Podington Bear; Podcast editing and production: Podigy, Sean Sanders]